Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular ...

In previous treat-to-target trials, adjustments to the dose of basal insulin have been made at least weekly, according to ...

Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg ...

Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry toward higher levels of integrated control by consolidated profit-seeking ...

Musunuru and colleagues 1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl ...

A 63-year-old woman was evaluated for dyspnea and edema. Soft-tissue thickening was noted in the retroperitoneum and mediastinum and around the heart and vessels. A diagnosis was made.

One of the more difficult decisions for patients with poorly controlled type 2 diabetes, as well as for their clinicians, is ...

We conducted a phase 2, double-blind, randomized, placebo-controlled, dose-ranging trial that included 11 groups as two cohorts. Participants with obesity (obesity cohort) were randomly assigned ...

Chronic meningitis is broadly characterized as infectious or noninfectious (Table 1). Geographic region of residence, travel, immune status, and underlying illnesses are the initial building ...

In the emergency department, the patient described the pain as sharp and rated it at 8 on a scale of 0 to 10 (with 10 indicating the most severe pain). The pain was worst in the epigastrium and in ...

Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical therapy, is typically recommended; surgery is considered in some cases.

Transcatheter aortic-valve replacement (TAVR) is an established treatment for patients with aortic stenosis across the spectrum of surgical risk. 1-9 Embolization of debris from the valve or the ...