Russia warned against efforts to force a regime change in Iran and said it would react “very negatively” if Iran’s Supreme Leader Ayatollah Khamenei were killed, raising concerns of a broader escalation in the Israel-Iran conflict as European leaders came together with Iran on Friday for a diplomatic meeting.

Oil prices rose on Thursday as a week-old air war between Israel and Iran escalated and uncertainty about potential U.S. involvement kept investors on edge. Brent crude futures were up $1.48, or 1.9%,

Israel and Iran have struck at one another again a week into their war as President Donald Trump weighs U.S. involvement and new diplomatic efforts appear to be taking place.

Iran and Israel traded attacks early Thursday as their war continued to intensify nearly a week after it began. Israel expressed outrage at an Iranian missile striking the largest hospital in southern Israel.

Iran's Foreign Minister Abbas Araghchi has called on the international community to condemn Israel's attacks on his country. "Any justification for this unjust and criminal war would be tantamount to complicity,