The United States said it did not support recent Israeli strikes on Syria and had made clear its displeasure, while Syrian leader Ahmed al-Sharaa accused Israel of trying to fracture his country.

Israel said it "struck the entrance of the Syrian regime's military headquarters" and warns of more "painful blows".

Violence in Syria's Druze province has triggered Israeli military action, complicating relations with Turkey and creating a power vacuum that Iran could exploit.

Several days of bitter sectarian fighting in the south of Syria has brought the fledgling government in Damascus dangerously close to direct conflict with Israel, after Israeli warplanes launched strikes against government buildings in the Syrian capital, Damascus, on July 16.

Israel carried out heavy airstrikes in the heart of Damascus on Wednesday, hitting Syrian Defense Ministry headquarters and an area near the presidential palace.

Republican congressman and Israel caucus co-chair Joe Wilson rebukes Israeli military strikes on Syria, calling them insulting to Trump's recent diplomatic efforts in the region.

The Israel Defense Forces (IDF) said the Damascus headquarters served as a command center for deploying regime forces to Suwayda, a southern Syrian region gripped by days of deadly clashes between government troops, Druze militias, and Bedouin groups.

That afternoon, Netanyahu and Katz ordered the Israeli military to once again attack government forces and weaponry in Suweida. They said they were working to prevent them from harming the Druze and to "ensure the demilitarisation" of areas near Israel's border.

A view of a destroyed building, after powerful airstrikes shook Damascus on Wednesday, targeting the defense ministry, as Israel vowed to destroy Syrian government forces attacking Druze communities in southern Syria and demanded their withdrawal,