After missing last week because of a hamstring injury, San Francisco 49ers running back Isaac Guerendo is set to play Monday night against the Detroit Lions. Guerendo, who has been listed as limited in practice this week with foot and hamstring issues,

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week's game with a hamstring injury, does not have

The San Francisco 49ers’ practice schedule began a day later than normal with a Monday night showdown against the Detroit Lions coming up in Week 17. Their practice report opened with some good news on the injury front. Running back Isaac Guerendo returned as a limited participant after missing all of Week 16 with a hamstring injury.