Confirmed team news, predicted lineup and injury latest for Premier League - Ruben Amorim could make changes as a busy schedule continues

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This evening’s match presents the perfect chance to make a positive start, as they face a Southampton side who sit bottom of the table with just six points so far this season. The Saints’ struggles have continued even since the arrival of new manager Ivan Juric,

Manchester United hope to win their first Premier League match in a month when they host last-place Southampton.